Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TM4SF1 Antibody

Boster Bio Anti-TM4SF1 Antibody (Catalog # A10368) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.

Synonyms

L6, H-L6, M3S1, TAAL6, Transmembrane 4 L6 family member 1, Membrane component chromosome 3 surface marker 1

Gene Name

TM4SF1

UniProt

P30408

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least three isoforms of TM4SF1 are known to exist; this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.

Immunogen

TM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1. The immunogen is located within the first 50 amino acids of TM4SF1.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Cancer, Cell Cycle

Purification

TM4SF1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Molecular Weight

21632 MW

Shipping Conditions

Available

Storage Conditions

TM4SF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10368

Product MSDS

https://www.bosterbio.com/msds?sku=A10368

Fragment

IgG

Other Gene Names

Transmembrane 4 L six family member 1

Subcellular Location

Membrane; Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519) .

Protein Name

Transmembrane 4 L six family member 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Anti-PCTP Antibody
MBS8323223-01 0.03 mL

Anti-PCTP Antibody

Ask
View Details
Anti-PCTP Antibody
MBS8323223-02 0.05 mL

Anti-PCTP Antibody

Ask
View Details
Anti-PCTP Antibody
MBS8323223-03 0.1 mL

Anti-PCTP Antibody

Ask
View Details
Anti-PCTP Antibody
MBS8323223-04 0.2 mL

Anti-PCTP Antibody

Ask
View Details
Anti-PCTP Antibody
MBS8323223-05 5x 0.2 mL

Anti-PCTP Antibody

Ask
View Details
CD31 (PECAM1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C2]
TA504862AM 100 µL

CD31 (PECAM1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1C2]

Ask
View Details