Anti-Prolyl 3-hydroxylase OGFOD1 OGFOD1 Antibody

Boster Bio Anti-Prolyl 3-hydroxylase OGFOD1 OGFOD1 Antibody (Catalog # A09074) . Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

OGFOD1, a member of the 2-OG-Fe (II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.

Synonyms

TPA1, KIAA1612, TPA1, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, Termination and polyadenylation 1 homolog

Gene Name

OGFOD1

UniProt

Q8N543

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

OGFOD1 antibody is predicted to not cross-react with other TPA1 protein family members. At least two isoforms are known to exist; this antibody will only detect the larger isform.

Immunogen

OGFOD1 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human OGFOD1. The immunogen is located within the first 50 amino acids of OGFOD1.

Clonality

Polyclonal

Applications

ELISA, WB, IF

Field of Research

Apoptosis

Purification

OGFOD1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation.

Molecular Weight

63246 MW

Shipping Conditions

Available

Storage Conditions

OGFOD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.