Anti-LRRTM1 Antibody

Boster Bio Anti-LRRTM1 Antibody (Catalog # A08006) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.

Synonyms

Leucine-rich repeat transmembrane neuronal protein 1

Gene Name

LRRTM1

UniProt

Q86UE6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

LRRTM1 antibody is predicted to not cross-react with other LRRTM family members.

Immunogen

LRRTM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM1. The immunogen is located within amino acids 450 - 500 of LRRTM1.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in forebrain regions including thalamus and cerebral cortex.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Neuroscience

Purification

LRRTM1 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level. .

Molecular Weight

58641 MW

Shipping Conditions

Available

Storage Conditions

LRRTM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.