Anti-NALP8 NLRP8 Antibody
Boster Bio Anti-NALP8 NLRP8 Antibody (Catalog # A15112) . Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Background
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
Synonyms
PAN4, NALP8, NOD16, CLR19.2, PAN4, NACHT, LRR and PYD domains-containing protein 8, Nucleotide-binding oligomerization domain protein 16
Gene Name
NLRP8
UniProt
Q86W28
Host
Rabbit
Reactivity
Human
Immunogen
NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8. The immunogen is located within amino acids 130 - 180 of NALP8.
Clonality
Polyclonal
Applications
ELISA, WB
Field of Research
Innate Immunity
Purification
NALP8 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Involved in inflammation. .
Molecular Weight
119430 MW
Shipping Conditions
Available
Storage Conditions
NALP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
NLR family, pyrin domain containing 8
Subcellular Location
Cytoplasm .
Protein Name
NLR family, pyrin domain containing 8
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