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Anti-NOD4 NLRC5 Antibody

Boster Bio Anti-NOD4 NLRC5 Antibody (Catalog # A04481) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Synonyms

NOD4, NOD27, CLR16.1, NOD4, Protein NLRC5, Nucleotide-binding oligomerization domain protein 27

Gene Name

NLRC5

UniProt

Q86WI3

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

NOD4 antibody is predicted to not cross-react with other members of the NOD family of proteins.

Immunogen

NOD4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NOD4. The immunogen is located within amino acids 20 - 70 of NOD4.

Clonality

Polyclonal

Tissue Specificity

Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.

Applications

ELISA, WB, ICC, IF

Field of Research

Innate Immunity

Purification

NOD4 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.

Molecular Weight

204595 MW

Shipping Conditions

Available

Storage Conditions

NOD4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04481

Product MSDS

https://www.bosterbio.com/msds?sku=A04481

Fragment

IgG

Other Gene Names

NLR family, CARD domain containing 5

Subcellular Location

Cytoplasm

Protein Name

NLR family, CARD domain containing 5

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