Anti-SH3RF2 Antibody
Boster Bio Anti-SH3RF2 Antibody (Catalog # A11489) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.
Synonyms
HEPP1, POSHER, RNF158, PPP1R39, Putative E3 ubiquitin-protein ligase SH3RF2, Heart protein phosphatase 1-binding protein, HEPP1
Gene Name
SH3RF2
UniProt
Q8TEC5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SH3RF2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SH3RF2. The immunogen is located within the last 50 amino acids of SH3RF2.
Clonality
Polyclonal
Tissue Specificity
Heart (at protein level) . Heart and testis. In the heart, present in the apex, left atrium, right atrium, left ventricle and right ventricle, but not in the aorta.
Applications
ELISA, WB, IHC-P, IF
Field of Research
Signal Transduction
Purification
SH3RF2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential) . May play a role in cardiac function.
Molecular Weight
79320 MW
Shipping Conditions
Available
Storage Conditions
SH3RF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
SH3 domain containing ring finger 2
Protein Name
SH3 domain containing ring finger 2
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