Anti-Transmembrane protein 184A TMEM184A Antibody

TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.

TMEM184A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human TMEM184A. The immunogen is located within the last 50 amino acids of TMEM184A.

Acts as a heparin receptor in vascular cells (By similarity) . May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity) .