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Anti-PAK4-inhibitor INKA1 FAM212A Antibody

Selected Variant

A18696

Size: 0.1 mg

Boster Bio Anti-PAK4-inhibitor INKA1 FAM212A Antibody (Catalog # A18696) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1) . FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1) . In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2) .

Synonyms

Family with sequence similarity 212 member A, INKA1, C3orf54

Gene Name

FAM212A

UniProt

Q96EL1

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.

Immunogen

FAM212A antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FAM212A. The immunogen is located within the last 50 amino acids of FAM212A.

Clonality

Polyclonal

Applications

ELISA, WB

Field of Research

Stem Cells, Neuroscience

Purification

FAM212A antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Inhibitor of the serine/threonine-protein kinase PAK4 (PubMed:26607847) . Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity (PubMed:26607847) .

Molecular Weight

31328 MW

Shipping Conditions

Available

Storage Conditions

FAM212A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Fragment

IgG

Other Gene Names

Family with sequence similarity 212 member A

Subcellular Location

Nucleus

Protein Name

Family with sequence similarity 212 member A

Price

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