Anti-SLAIN2 Antibody

Boster Bio Anti-SLAIN2 Antibody (Catalog # A11030) . Tested in ELISA, IHC-P applications. This antibody reacts with Human.

Product Specifications

Background

SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

Synonyms

KIAA1458, KIAA1458, SLAIN motif-containing protein 2

Gene Name

SLAIN2

UniProt

Q9P270

Host

Rabbit

Reactivity

Human

Cross Reactivity

SLAIN2 antibody is predicted not to cross-react with SLAIN1.

Immunogen

SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2. The immunogen is located within amino acids 70 - 120 of SLAIN2.

Clonality

Polyclonal

Tissue Specificity

Widely expressed with highest levels in adult liver, testis and ovary, and lowest levels in adult pancreas and spleen and in fetal brain.

Applications

ELISA, IHC-P

Field of Research

Stem Cells

Purification

SLAIN2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.

Molecular Weight

62543 MW

Shipping Conditions

Available

Storage Conditions

SLAIN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.