Anti-GNPDA2 Antibody

Boster Bio Anti-GNPDA2 Antibody (Catalog # A06565) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.

Synonyms

GNP2, SB52, GNP2, Glucosamine-6-phosphate isomerase 2, Glucosamine-6-phosphate deaminase 2, GNPDA 2

Gene Name

GNPDA2

UniProt

Q8TDQ7

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

GNPDA2 antibody is predicted to not cross-react with GNPDA1.

Immunogen

GNPDA2 antibody was raised against an 8 amino acid synthetic peptide near the carboxy terminus of human GNPDA2. The immunogen is located within the last 50 amino acids of GNPDA2.

Clonality

Polyclonal

Tissue Specificity

Highest expression in heart, skeletal muscle and brain. Lower expression in all other tissues.

Applications

ELISA, WB, ICC, IF

Field of Research

Homeostasis

Purification

GNPDA2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

Molecular Weight

31085 MW

Shipping Conditions

Available

Storage Conditions

GNPDA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.