Anti-LASS6 CERS6 Antibody

Boster Bio Anti-LASS6 CERS6 Antibody (Catalog # A07033) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.

Synonyms

CERS5, LASS6, Ceramide synthase 6, LAG1 longevity assurance homolog 6, CerS6

Gene Name

CERS6

UniProt

Q6ZMG9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.

Immunogen

LASS6 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human LASS6. The immunogen is located within the last 50 amino acids of LASS6.

Clonality

Polyclonal

Tissue Specificity

Specifically expressed in brain.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

LASS6 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May be involved in sphingolipid synthesis or its regulation. .

Molecular Weight

44890 MW

Shipping Conditions

Available

Storage Conditions

LASS6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.