Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody

Boster Bio Anti-SLIT and NTRK-like protein 5 Slitrk5 Antibody (Catalog # A10564) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Synonyms

LRRC11, bA364G4.2, KIAA0918, LRRC11, SLIT and NTRK-like protein 5, Leucine-rich repeat-containing protein 11

Gene Name

SLITRK5

UniProt

O94991

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Immunogen

Slitrk5 antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slitrk5. The immunogen is located within amino acids 310 - 360 of Slitrk5.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Neuroscience

Purification

Slitrk5 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Suppresses neurite outgrowth. .

Molecular Weight

107486 MW

Shipping Conditions

Available

Storage Conditions

Slitrk5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.