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Anti-TRPC3 Antibody

Boster Bio Anti-TRPC3 Antibody (Catalog # A01472-1) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.

Product Specifications

Background

2+

Synonyms

TRP3, TRP3, Short transient receptor potential channel 3, Transient receptor protein 3, TrpC3

Gene Name

TRPC3

UniProt

Q13507

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody may cross-react with TRPC6 and TRPC7.

Immunogen

TRPC3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human TRPC3. The immunogen is located within amino acids 120 - 170 of TRPC3.

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.

Applications

ELISA, WB, IHC-P

Field of Research

Signal Transduction, Neuroscience, Infectious Diseases

Purification

TRPC3 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.

Molecular Weight

96009 MW

Shipping Conditions

Available

Storage Conditions

TRPC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Other Gene Names

Transient receptor potential cation channel, subfamily C, member 3

Subcellular Location

Membrane; Multi-pass membrane protein.

Prediction Reactivity

Rat

Protein Name

Transient receptor potential cation channel, subfamily C, member 3

Curated Selection

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