MKT-077
MKT-077 (FJ-776), a highly water-soluble mitochondrial dye, has significant antitumor activity[1]. MKT-077 exhibits low cytotoxicity, and inhibits broad-spectrum human cancer cell lines (colon cancer, breast cancer, pancreatic cancer) . MKT-077 inhibits the growth of tumor in nude mice enograft tumor model. Ex/Em=488/543 nm[2].
Product Specifications
CAS Number
147366-41-4
Product Name Alternative
FJ-776
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye; HSP
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MKT-077.html
Purity
98.77
Solubility
DMSO : 56.67 mg/mL (ultrasonic)
Smiles
CN(C1=CC=CC=C1S/2)C2=C3C(N(CC)/C(S\3)=C/C4=[N+](CC)C=CC=C4)=O.[Cl-]
Molecular Formula
C21H22ClN3OS2
Molecular Weight
432.00
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
Phase 2
Isoform
HSP70
Available Sizes
Frequently Asked Questions
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