Anti-Bcl-B BCL2L10 Antibody

Boster Bio Anti-Bcl-B BCL2L10 Antibody (Catalog # A07380) . Tested in ELISA, WB, ICC applications. This antibody reacts with Human.

Product Specifications

Background

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

Synonyms

Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10

Gene Name

BCL2L10

UniProt

Q9HD36

Host

Rabbit

Reactivity

Human

Immunogen

Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B. The immunogen is located within amino acids 90 - 140 of Bcl-B.

Clonality

Polyclonal

Tissue Specificity

Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney.

Applications

ELISA, WB, ICC

Field of Research

Apoptosis

Purification

Bcl-B Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.

Molecular Weight

21973 MW

Shipping Conditions

Available

Storage Conditions

Bcl-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.