Anti-ARC NOL3 Antibody
Boster Bio Anti-ARC NOL3 Antibody (Catalog # A03991) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.
Product Specifications
Background
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
Synonyms
ARC, FCM, MYP, NOP, NOP30, ARC, Nucleolar protein 3, Apoptosis repressor with CARD, Myp
Gene Name
NOL3
UniProt
O60936
Host
Rabbit
Reactivity
Human
Immunogen
ARC antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ARC. The immunogen is located within the last 50 amino acids of ARC.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.
Applications
ELISA, WB, IHC-P
Field of Research
Apoptosis
Purification
ARC Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Isoform 1: May be involved in RNA splicing.
Molecular Weight
22629 MW
Shipping Conditions
Available
Storage Conditions
ARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Other Gene Names
Nucleolar protein 3 (apoptosis repressor with CARD domain)
Subcellular Location
Isoform 1: Nucleus, nucleolus
Protein Name
Nucleolar protein 3 (apoptosis repressor with CARD domain)
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
