KRAS G12D inhibitor 25
KRAS G12D inhibitor 25 (Compound 148) is an inhibitor for KRAS G12C and HSP90α with IC50 of EC50 of ERBB2 with a DC50 of 0.1-1 μM[1].
Product Specifications
CAS Number
[2768099-61-0]
UNSPSC
12352101
Target
EGFR; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; JAK/STAT Signaling; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-25.html
Smiles
C=CC(N1CCN(C[C@@H]1CC#N)C2=NC(OC[C@@H]3CCCN(C3)C(C4CCN(CC4)CC5=CC=C(C=C5)N6C(O)=NN=C6C7=C(C=C(C(C(C)C)=C7)O)O)=O)=NC8=C2CCN(C8)C9=C%10C(Cl)=CC=CC%10=CC=C9)=O
Molecular Formula
C56H62ClN11O6
Molecular Weight
1020.61
References & Citations
[1]Ying W, et al., Methods and compositions for targeting protein degradation. CN116615422A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4565305 3x 1.0 µg
Orc6 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details 
