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EC5026

EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain[1].

Product Specifications

CAS Number

[1809885-32-2]

Product Name Alternative

BPN-19186

UNSPSC

12352005

Hazard Statement

H301

Target

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ec5026.html

Purity

98.13

Solubility

DMSO : ≥ 250 mg/mL

Smiles

O=C(NC1CCN(C([C@@H](C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2

Molecular Formula

C18H23F4N3O3

Molecular Weight

405.39

Precautions

H301

References & Citations

[1]EicOsis Announces FDA Acceptance of IND Application for EC5026, the First Soluble Epoxide Hydrolase Inhibitor to Treat Pain.2019.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

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