β-Casomorphin, bovine

β-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay[1].

Product Specifications

CAS Number

[72122-62-4]

Product Name Alternative

β-Casomorphin-7 (bovine) ; Bovine β-casomorphin-7

UNSPSC

12352209

Target

Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/_beta_-Casomorphin,_bovine.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

O=C(N(CCC1)[C@@H]1C(NCC(N(CCC2)[C@@H]2C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)[C@@H](NC([C@H](CCC3)N3C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O)CC5=CC=CC=C5

Molecular Formula

C41H55N7O9

Molecular Weight

789.92

References & Citations

[1]Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28 (17) :1903-9.|[2]Zoghbi S, et al. β-casomorphin-7-7 regulates the secretion and expression of gastrointestinal mucins through a μ-opioid pathway. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290 (6) :G1105-13.|[3]Zhang W, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8 (5) :e63472.