Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-VPS11 Rabbit Monoclonal Antibody

Boster Bio Anti-VPS11 Rabbit Monoclonal Antibody catalog # M05575. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Drebrin; Developmentally-regulated brain protein; DBN1; D0S117E

Gene Name

Drebrin

UniProt

Q9H270

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human VPS11

Clonality

Monoclonal

Clone

Clone: 22V84

Tissue Specificity

Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level) . .

Applications

WB, IHC, Flow Cytometry

Field of Research

Signal Transduction, Cytoskeleton, Cytoskeleton/ECM, Actin Assembly, Actin, etc., Microfilaments

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M05575

Product MSDS

https://www.bosterbio.com/msds?sku=M05575

Fragment

IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>FC 1:80

Other Gene Names

VPS11

Subcellular Location

Cytoplasm . Cytoplasm, cell cortex . Cell junction . Cell projection . Cell projection, growth cone . In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400) . Colocalized with DBN1, RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity) . .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

mmu-miR-3073b-3p mimic
HY-R02934-01 5 nmol

mmu-miR-3073b-3p mimic

Ask
View Details
mmu-miR-3073b-3p mimic
HY-R02934-02 20 nmol

mmu-miR-3073b-3p mimic

Ask
View Details
Rabbit Monoclonal FABP1/L-FABP Antibody (FABP1/8521R) [Alexa Fluor 750]
NBP3-21003AF750 0.1 mL

Rabbit Monoclonal FABP1/L-FABP Antibody (FABP1/8521R) [Alexa Fluor 750]

Ask
View Details
MART-1 / Melan-A Recombinant Antibody
V5603-20UG 20 µg

MART-1 / Melan-A Recombinant Antibody

Ask
View Details
Recombinant Sclerotinia sclerotiorum Cell division cycle protein 123 (CDC123)
MBS1165693-01 0.02 mg (E-Coli)

Recombinant Sclerotinia sclerotiorum Cell division cycle protein 123 (CDC123)

Ask
View Details
Recombinant Sclerotinia sclerotiorum Cell division cycle protein 123 (CDC123)
MBS1165693-02 0.02 mg (Yeast)

Recombinant Sclerotinia sclerotiorum Cell division cycle protein 123 (CDC123)

Ask
View Details