MART-1 / Melan-A Recombinant Antibody
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1), MLANA or Melan-A. MART-1/MLANA is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1/MLANA is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Product Specifications
UniProt
Q16655
Host
Mouse
Immunogen
Recombinant full-length human MART-1/Melan-A protein was used as the immunogen for the recombinant MLANA antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Type
Recombinant
Applications
IHC-P, WB
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant MLANA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant MLANA antibody is available for research use only.
CAS Number
9000-83-3
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
