Human AREG Protein

AREG is a one-way membrane protein consisting of 252 amino acids. AREG belongs to AREG family and contains an EGF-like domain. AREG is expressed in many tissues, including ovary, placenta, lung, kidney, stomach, colon and breast. It is related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α) . As an EGF-related growth factor, AREG interacts with EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibit the growth of some invasive cancer cell lines.

Product Specifications

Background

AREG is a one-way membrane protein consisting of 252 amino acids. AREG belongs to AREG family and contains an EGF-like domain. AREG is expressed in many tissues, including ovary, placenta, lung, kidney, stomach, colon and breast. It is related to epidermal growth factor (EGF) and transforming growth factor α (TGF-α) .As an EGF-related growth factor, AREG interacts with EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibit the growth of some invasive cancer cell lines

Product Name Alternative

AR; SDGF; AREGB; CRDGF

Gene ID

374

Accession Number

P15514

Tag

AREG

Type

Cytokines and proteins

Applications

No tag

Purity

> 95 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

11.4 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized recombinant Human AREG protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human AREG consists of 98 amino acids and predicts a molecular mass of 11.4 kDa.

Formulation

Lyophilized from sterile 20mM Tris, 800mM NaCl, pH 7.4.

Applications Notes

Human

Other Product Names

AR; SDGF; AREGB; CRDGF

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human AREG protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.