Mouse Flt-3 Ligand protein , His tag (Animal-Free)
Fms-related tyrosine kinase-3 ligand (Flt-3 Ligand) is a protein which is encoded by the Flt3lg gene in mouse. As an important regulator of hematopoiesis, Flt-3 ligand has a tyrosine-protein kinase activity that stimulate the proliferation of hematopoietic progenitor cells of both lymphoid and myeloid origin. Flt-3 ligand can synergistically increase the proliferation of immature progenitors with other cytokines such as GM-CSF, G-CSF, IL-3, EPO, IL-11, IL-12, IL-6 or TPO. Flt-3 ligand is expressed by a variety of hematopoietic progenitor cells including immature hematopoietic and marrow stromal cells.
Product Specifications
Background
Product Name Alternative
Fetal liver kinase 2, FLK-2
Accession Number
P49772
Tag
Flt-3 Ligand
Type
Cytokines and proteins
Applications
His tag
Purity
>98% as determined by SDS-PAGE.
Activity
Measure by its ability to induce proliferation in BaF3 cells transfected with Mouse Flt-3 Ligand.The ED50 for this effect is <2 ng/mL
Molecular Weight
The protein has a calculated MW of 19.3 kDa.The protein migrates as 19 kDa under reducing condition (SDS-PAGE analysis) .
Precautions
Features & Benefits
Endotoxin:<0.1 EU per 1 μg of the protein by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Protein Length
The secreted Mouse Flt-3 Ligand consists of 162 amino acids and has a predicted molecular mass of 19.3 kDa
Formulation
The protein was Lyophilized from sterile PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Applications Notes
Mouse
Other Product Names
Fetal liver kinase 2, FLK-2
Recommended Usage
Preparation
E. coli
AA Sequence
Amino acid sequence derived from Mouse Flt-3 Ligand (Gly27-Arg188) (P49772) with 6xHis tag at the C-terminus was expressed
Available Sizes
Frequently Asked Questions
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