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Human CXCL1 Protein

Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity.

Product Specifications

Background

Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis

Product Name Alternative

FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1

Gene ID

2919

Accession Number

P09341

Tag

CXCL1

Type

Cytokines and proteins

Applications

No tag

Purity

> 96 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

7.9 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1 EU per μg of the protein as determined by the LAL method

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized recombinant Human CXCL1 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Human CXCL1 consists of 73 amino acids and predicts a molecular mass of 7.9 kDa.

Formulation

Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 8.0.

Applications Notes

Human

Other Product Names

CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human CXCL1 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions

Preparation

E. coli

AA Sequence

Amino acid sequence derived from Human CXCL1 (P09341) (Ala35-Asn107) was expressed.

Available Sizes

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