Human TGF-β3 Protein
Human TGF-β3 Protein, expressed in E. coli
Product Specifications
Background
TGF-β3 (transforming growth factor-β3) is a member of a TGF-beta superfamily subgroup that performs many cellular functions. TGF-β3 has a role in embryogenesis and cell differentiation. TGF-β3 also plays a critical role in palatogenesis, the wound healing process.TGF-β3 is important in embryonic development, scarless repair of injury in the embryo, adult wound healing and tissue homeostasis. It has an important role in regulating cell migration, angiogenesis, epithelial-mesenchymal transition, apoptosis, modulation of immune function, extracellular matrix (ECM) production and the regulation of ECM remodelling; biological processes that are often required for tumour growth and maintenance.
Product Name Alternative
TGF-β3; ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor beta 3
Gene ID
7043
Accession Number
P10600
Tag
TGF-β3
Type
Cytokines and proteins
Applications
No tag
Purity
> 95 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
12.7 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 1 EU per μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized recombinant Human TGF-β3 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles
Protein Length
The recombinant human TGF-β3 consists of 112 amino acids and predicts a molecular mass of 12.7 kDa.
Formulation
Lyophilized from 20 mM Tris-HCl pH 8.0, 50 mM NaCl, 0.5 mM EDTA.
Applications Notes
Human
Other Product Names
Human TGF-β3 Protein; TGF-β3; ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor beta 3
Recommended Usage
Centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant human TGF-β 3 protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
http://www.uniprot.org/uniprot/P10600
AA Sequence
Amino acid sequence derived from human TGF-β3 (Ala301-Ser412) was expressed.
Available Sizes
Curated Selection
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