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Human TGF-β3 Protein

Human TGF-β3 Protein, expressed in E. coli

Product Specifications

Background

TGF-β3 (transforming growth factor-β3) is a member of a TGF-beta superfamily subgroup that performs many cellular functions. TGF-β3 has a role in embryogenesis and cell differentiation. TGF-β3 also plays a critical role in palatogenesis, the wound healing process.TGF-β3 is important in embryonic development, scarless repair of injury in the embryo, adult wound healing and tissue homeostasis. It has an important role in regulating cell migration, angiogenesis, epithelial-mesenchymal transition, apoptosis, modulation of immune function, extracellular matrix (ECM) production and the regulation of ECM remodelling; biological processes that are often required for tumour growth and maintenance.

Product Name Alternative

TGF-β3; ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor beta 3

Gene ID

7043

Accession Number

P10600

Tag

TGF-β3

Type

Cytokines and proteins

Applications

No tag

Purity

> 95 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

12.7 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized recombinant Human TGF-β3 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant human TGF-β3 consists of 112 amino acids and predicts a molecular mass of 12.7 kDa.

Formulation

Lyophilized from 20 mM Tris-HCl pH 8.0, 50 mM NaCl, 0.5 mM EDTA.

Applications Notes

Human

Other Product Names

Human TGF-β3 Protein; TGF-β3; ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor beta 3

Recommended Usage

Centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant human TGF-β 3 protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Preparation

E. coli

Accession Number URL

http://www.uniprot.org/uniprot/P10600

AA Sequence

Amino acid sequence derived from human TGF-β3 (Ala301-Ser412) was expressed.

Available Sizes

Curated Selection

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