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Human BMP-13 Protein

Human BMP-13 Protein, expressed in E. coli

Product Specifications

Background

Bone morphogenetic protein (BMP) also known as growth differentiation factor, which belongs to the transforming growth factor beta (TGF-beta) superfamily. These factors are produced as inactive preproproteins which are subsequently cleaved and assembled into active secreted homodimers. BMP-13 has a central role in regulating apoptosis during retinal development, and also controls proliferation and cellular differentiation in the retina and bone formation. The recombinant human BMP-13 is a 13.5 kDa protein consisting of 120 amino acids polypeptide chains under reducing conditions.

Product Name Alternative

Bone morphogenetic protein 13

Gene ID

392255

Accession Number

P49278

Tag

BMP-13

Type

Cytokines and proteins

Applications

No tag

Purity

> 96 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

13.5 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized recombinant Human BMP-13 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human BMP-13 consists of 120 amino acids and predicts a molecular mass of 13.5 kDa.

Formulation

Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 7.0.

Applications Notes

Human

Other Product Names

Human BMP-13 Protein; Bone morphogenetic protein 13; BMP-13

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human BMP-13 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Preparation

E. coli

Accession Number URL

http://www.uniprot.org/uniprot/P49278

AA Sequence

Amino acid sequence derived from Human BMP-13 (NP_001001557.1) (Thr335-Arg454) was expressed.

Available Sizes

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