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Human/Mouse/Rat Activin A Protein

Human/Mouse/Rat Activin A Protein, expressed in E. coli

Product Specifications

Background

Activin A, a member of TGF-β superfamily, is a disulfide-linked dimer protein, which was originally purified from gonadal fluid as protein to stimulate the release of pituitary follicle-stimulating hormone (FSH) . Inhibins are involved in regulating many different functions, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythrocyte differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Many studies have shown that it can play a significant role in inducing islet β cell differentiation under the combined action of other factors. The recombinant Human Activin A has sequence identity with Mouse and Rat Activin A protein.

Product Name Alternative

RHuActivin A; Inhibin beta A chain; INHBA; Activin A ACV-A

Gene ID

3624

Accession Number

P08476

Tag

Activin A

Type

Cytokines and proteins

Applications

No tag

Purity

> 97 % as determined by SDS-PAGE

Activity

Testing in progress

Molecular Weight

13.0 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: < 1 EU per μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized Human/Mouse/Rat Activin A protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Protein Length

The Human/Mouse/Rat Activin A consists of 116 amino acids and predicts a molecular mass of 13.0 kDa.

Formulation

Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 8.0.

Applications Notes

Human/Mouse/Rat

Other Product Names

Activin A; rHuActivin A; Inhibin beta A chain; INHBA; Activin A ACV-A

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human/Mouse/Rat-Activin A protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Preparation

E. coli

Accession Number URL

http://www.uniprot.org/uniprot/P08476

AA Sequence

Amino acid sequence derived from Human Activin A (NP_002183.1) (Gly311-Ser426) was expressed.

Available Sizes

Curated Selection

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