Glycididazole (sodium)

Glycididazole sodium (Sodium glycididazole) is a radiosensitizer. Glycididazole sodium increases the sensitivity of nasopharyngeal carcinoma cells to radiation, through increaased DNA damage and enhanced apoptosis in NPC cells[1]

Product Specifications

CAS Number

[173357-17-0]

Product Name Alternative

Sodium glycididazole

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glycididazole-sodium.html

Smiles

O=C(O[Na])CN(CC(OCCN1C([N+]([O-])=O)=CN=C1C)=O)CC(OCCN2C([N+]([O-])=O)=CN=C2C)=O

Molecular Formula

C18H22N7NaO10

Molecular Weight

519.40

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Min X, et al., The Radiosensitization of Sodium Glycididazole on Nasopharyngeal Carcinoma Cells via Enhancing DNA Damage and Promoting Apoptosis. J Cancer. 2019 Jan 1;10 (2) :305-312.