Anti-Prostein Antibody

Rabbit Polyclonal Antibody specific to Prostein

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Prostate cancer-associated protein 6, Prostein

Gene Name

SLC45A3

NCBI Gene ID

UniProt

Q96JT2

Cellular Locus

Membrane, Multi-pass membrane protein

Host

Rabbit

Reactivity

Human

Immunogen

N-terminal sequence ITYVPPLLLEVGVEE and C-terminal Sequence FATQVVFDKSDLAKYSA of human prostein.

Target Antigen

Solute carrier family 45 member 3

Target

Prostein

Clonality

Polyclonal

Type

Antibody

Applications

WB, ELISA

Field of Research

Cancer research

Purification Method

Purified by Protein A affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Additionnal Information

Immunoblotting: use at 1:500-1:1,000 dilution <br><br>ELISA: use at 1:1,000-1:5,000 dilution.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.

Specificity

This antibody recognizes human prostein (55 kD).

Formulation

PBS.

Target Background

Prostein is a novel prostate-specific protein expressed in normal and malignant prostate tissues. This protein appears to be a type IIIa plasma membrane protein with a cleavable signal peptide and 11 transmembrane-spanning regions. Prostein expression is androgen responsive since treatment of LNCaP cells with androgen up-regulates prostein message and protein expression levels. Thus, prostein is a prostate-specific marker whose detection and quantitation may be useful in diagnosing and monitoring prostate cancer.