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Chlorprothixene (Standard)

Chlorprothixene (Standard) is the analytical standard of Chlorprothixene. This product is intended for research and analytical applications. Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].

Product Specifications

CAS Number

113-59-7

UNSPSC

12352005

Target

Bacterial; Dopamine Receptor; Histamine Receptor; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/chlorprothixene-standard.html

Solubility

H2O : < 0.1 mg/mL

Smiles

CN(C)CC/C=C1C2=C(SC3=C\1C=CC=C3)C=CC(Cl)=C2

Molecular Formula

C18H18ClNS

Molecular Weight

315.86

References & Citations

[1]Y von Coburg, et al. Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorg Med Chem Lett. 2009 Jan 15;19 (2) :538-42.|[2]B L Roth, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268 (3) :1403-10.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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