SB-399885 hydrochloride

SB-399885 hydrochloride is a 5-HT6 receptor antagonist.

Product Specifications

CAS Number

[402713-81-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/SB-399885_hydrochloride.html

Purity

98.33

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Cl)=CC(Cl)=C3OC)=O.[H]Cl

Molecular Formula

C18H22Cl3N3O4S

Molecular Weight

482.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Monti JM, et al. Effects of the 5-HT6 receptor antagonists SB-399885 and RO-4368554 and of the 5-HT (2A) receptor antagonist EMD 281014 on sleep and wakefulness in the rat during both phases of the light-dark cycle. Behav Brain Res. 2011 Jan 1;216 (1) :381-8.