Bupivacaine
Bupivacaine is a NMDA receptor inhibitor. Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain[1][2][3].
Product Specifications
CAS Number
[38396-39-3]
UNSPSC
12352005
Hazard Statement
H300, H310, H330
Target
Calcium Channel; iGluR; Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/bupivacaine.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1N(CCCC)CCCC1)NC2=C(C)C=CC=C2C
Molecular Formula
C18H28N2O
Molecular Weight
288.43
Precautions
H300, H310, H330
References & Citations
+
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
NMDA Receptor
Citation 01
Cell. 2025 Oct 24:S0092-8674 (25) 01129-8.|Nat Commun. 2023 Jun 3;14 (1) :3224.|Stem Cell Res Ther. 2021 Feb 4;12 (1) :107.
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