Interphotoreceptor Retinoid Binding Protein Fragment (IRBP)

This 20-amino acid peptide, corresponding to residues 161-180 of Interphotoreceptor Retinoid-Binding Protein (IRBP), is a major pathogenic epitope. It is used to induce Experimental Autoimmune Uveitis (EAU) in animal models, serving as a critical tool for studying autoimmune eye disease mechanisms in both in vivo and in vitro research.