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Ac2-26

The annexin A1 mimetic peptide Ac2-26 demonstrates protective effects in preclinical models by modulating key inflammatory and apoptotic pathways. It has shown efficacy in attenuating diabetic nephropathy, sepsis-induced cardiomyopathy, and hepatic ischemia-reperfusion injury in mice through mechanisms involving p38MAPK/NF-κB, LXA4/PI3K/AKT, and IL-22/STAT3 signaling.

Product Specifications

Product Name Alternative

Ac2 26, Ac226, Ac-2-26, Ac2-26

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.78% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (0.65 mM) ; H2O:5 mg/mL (1.62 mM)

Molecular Weight

3089.43

Storage Conditions

Keep away from moisture | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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