Ac2-26
The annexin A1 mimetic peptide Ac2-26 demonstrates protective effects in preclinical models by modulating key inflammatory and apoptotic pathways. It has shown efficacy in attenuating diabetic nephropathy, sepsis-induced cardiomyopathy, and hepatic ischemia-reperfusion injury in mice through mechanisms involving p38MAPK/NF-κB, LXA4/PI3K/AKT, and IL-22/STAT3 signaling.
Product Specifications
Product Name Alternative
Ac2 26, Ac226, Ac-2-26, Ac2-26
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.78% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (0.65 mM) ; H2O:5 mg/mL (1.62 mM)
Molecular Weight
3089.43
Storage Conditions
Keep away from moisture | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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