HIF-1 alpha (556-574) TFA (1201633-99-9 free base)

This 19-mer peptide fragment of hypoxia-inducible factor-1 alpha (HIF-1α) contains the critical proline 564 residue essential for binding to the von Hippel-Lindau (VHL) E3 ligase. It is a key research tool for studying oxygen-sensing pathways, enabling in vitro binding assays and investigations into HIF-1 stabilization and degradation mechanisms relevant to cancer and ischemic disease models.