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Balixafortide

Balixafortide (POL6326) is a selective peptidic CXCR4 antagonist with sub-10 nM potency, effectively mobilizing hematopoietic stem/progenitor cells (HSPCs) . It demonstrates anti-cancer potential in research by inhibiting CXCR4-mediated β-arrestin recruitment and calcium signaling, showing >1000-fold selectivity over related receptors like CXCR7 in vitro and in vivo studies.

Product Specifications

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Molecular Weight

1864.14

Storage Conditions

-20°C

Notes

For research use only.

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