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UNC4976 TFA

UNC4976 TFA is a peptidomimetic CBX7 chromodomain positive allosteric modulator (PAM) . It functions by disrupting the specific recruitment of CBX7 to H3K27me3-marked genes while promoting its non-specific binding to DNA and RNA. This compound is a valuable chemical probe for studying Polycomb repressive complex 1 (PRC1) function in epigenetic regulation, applicable in both in vitro binding assays and cellular models.

Product Specifications

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation

Molecular Weight

961.12

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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