R18 TFA
R18 TFA is a potent 14-3-3 protein-protein interaction antagonist with a K_D of 70-90 nM. It disrupts the 14-3-3/Raf-1 complex, blocking 14-3-3's protective role and promoting Raf-1 deactivation. This peptide is a valuable tool for studying 14-3-3 signaling in cancer research and cellular regulation, applicable in both in vitro and cell-based assays.
Product Specifications
Field of Research
Immunology & Inflammation, Signal Transduction
Molecular Weight
2423.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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