[Ala17]-MCH TFA

[Ala17]-MCH TFA is a potent and selective MCHR1 agonist analog of Melanin-Concentrating Hormone, exhibiting sub-nanomolar affinity for MCHR1 (Kd=0.37 nM) with minimal binding to MCHR2. This high selectivity makes it a valuable pharmacological tool for investigating MCHR1-specific signaling pathways and functions in both in vitro and in vivo studies related to energy homeostasis, sleep, and mood regulation.