GR231118 TFA

GR231118 TFA is a potent and selective antagonist at the human NPY Y1 receptor (pKi 10.4) and a strong agonist at the human Y4 receptor. It exhibits weak agonism at Y2/Y5 receptors and high affinity for the mouse Y6 receptor. This peptide analogue is a valuable tool for investigating NPY receptor signaling in metabolic, cardiovascular, and neurological research models.