Lei-Dab7 TFA

Lei-Dab7 TFA is a potent and selective K Ca 2.2 (SK2) channel blocker with a K d of 3.8 nM, exhibiting >200-fold selectivity over related channels. This compound enhances theta-burst responses and long-term potentiation in hippocampal slices, making it a valuable tool for studying synaptic plasticity and SK2 channel function in neurological research.