Tat-NR2Baa TFA

Tat-NR2BAA TFA is an inactive control peptide for Tat-NR2B9c, containing a mutated tSXV motif that prevents PSD-95 binding. In contrast, the active Tat-NR2B9c peptide disrupts PSD-95 interactions with NR2A/NR2B-containing NMDARs, a mechanism studied in models of stroke and neuropathic pain.