Ac-KQL-AMC

Ac-KQL-AMC is a fluorogenic substrate that can be used to quantify Trypsin-like activity, resulting in detectable fluorescence when cleaved by the proteasome[1].

Product Specifications

CAS Number

[1104011-51-9]

UNSPSC

12352209

Target

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-kql-amc.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C2NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CCCCN)=O)CCC(N)=O)=O)CC(C)C)=O)=CC(OC1=C2)=O

Molecular Formula

C29H42N6O7

Molecular Weight

586.68

References & Citations

[1]Miyauchi S, et al. Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway. Cell Rep. 2023 May 30;42 (5) :112508.