α-Helical CRF (9-41) TFA

α-Helical CRF (9-41) is a potent synthetic CRF receptor antagonist, inhibiting ACTH release in vitro (0.5-5 μM) and in vivo (0.02-0.6 μmol/kg) . It is used in research on stress, anxiety (e.g., nicotine-conditioned models), and addictive behaviors (e.g., binge ethanol consumption), demonstrating efficacy in both rodent physiological and behavioral studies.