PMX-53 TFA
PMX-53 is a potent C5a receptor antagonist (IC50 = 0.3 μM) that inhibits C5a-induced MPO release in human PMNs in vitro. It demonstrates in vivo efficacy by reducing inflammation in rat Arthus reaction and Huntington's disease models, and attenuates atherosclerosis in ApoE-/- mice.
Product Specifications
Field of Research
Immunology & Inflammation; Stem Cell & Developmental Biology
Molecular Weight
896.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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