Gastric Inhibitory Peptide 1 (3-42) (human) TFA

GIP (3-42) is a DPP-4-generated GIP receptor antagonist. In ob/ob mice, it elevates blood glucose and reduces insulin, an effect replicated in vitro by inhibiting insulin secretion from BRIN-BD11 cells at 100 nM. This peptide is a valuable tool for studying incretin physiology and diabetes pathophysiology.