Tat-βsyn-degron TFA

Tat-βsyn-degron is a chimeric peptide designed to reduce α-synuclein levels. It combines a cell-penetrating Tat domain, a β-synuclein-derived binding motif, and a proteasomal targeting signal. This tool has demonstrated efficacy in reducing α-synuclein in primary neuronal cultures, supporting research in Parkinson's disease and synucleinopathy models.