Klotho-derived Peptide 1 (56-87) (human) TFA
KP1 (Klotho-derived peptide 1 (56-87) ) is a human Klotho fragment that inhibits TGF-β signaling by binding to TGFBR1/TGFBR2. It reduces fibrotic markers like fibronectin and α-SMA in vitro and ameliorates kidney injury and fibrosis in murine UUO and ischemia-reperfusion models, demonstrating therapeutic research potential for renal fibrosis.
Product Specifications
Field of Research
Immunology & Inflammation
Molecular Weight
3228.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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