IDR 1002

IDR 1002 is an innate defense regulator peptide that reduces bacterial burden and inflammation in murine sinusitis and lung infection models. It suppresses LPS-induced NF-κB and COX-2 while activating the p38/ERK/MSK1/CREB pathway, making it a valuable tool for researching host-directed therapies against bacterial infections in both in vivo and in vitro settings.